MMTB

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allopregnanolone biosynthesis

State Icon		Reaction	EC-Number	Confidence maximal confidence score from EnzymeDetector
		5alpha-pregnane-3beta-ol-20-one + NADP+ <=> H+ + 5alpha-dihydroprogesterone + NADPH	1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase 1.1.1.148 estradiol 17alpha-dehydrogenase 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase 1.1.1.278 3beta-hydroxy-5alpha-steroid dehydrogenase 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase	– – – – – – – – –
	BRENDA: BR47593; BS187716 KEGG: R07138; R08957 MetaCyc: 1.1.1.278-RXN; RXN66-567 SABIO-RK: 13071
		5alpha-dihydroprogesterone + NADP+ <=> progesterone + NADPH + H+	1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) 1.3.99.5 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)	– –
	BRENDA: BS258427 KEGG: R02208 MetaCyc: PROGESTERONE-5-ALPHA-REDUCTASE-RXN SABIO-RK: 2180

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